However, a full assessment will help determine what other treatment plans will be most beneficial to your pet. Administer maropitant citrate a minimum of two hours prior to travel with a small amount of food to mitigate vomiting associated with administration of the dose on an empty stomach; however, refrain from feeding a full meal prior to travel. Wash hands with soap and water after administering drug. In case of accidental eye exposure, flush with water for 15 minutes and seek medical attention. Some people who have tried the drug to their dog says there are several side effects when using cerenia for dogs upset stomach. by or on the order of a licensed veterinarian. Dogs allocated to the placebo group were treated using either an injectable placebo solution or placebo tablets once daily at the discretion of the clinician. Like any drug, Cerenia can have side effects, so its crucial to monitor your dogs behavior and contact your vet if you notice anything unusual. However, as with any medication, its essential to follow your veterinarians instructions carefully and monitor your dog for any adverse reactions. See also My Dog Ate a 300 mg Gabapentin? When a European field study tested dogs for adverse reactions from using Cerenia, 8 out of 107 dogs 8 developed drowsiness, lethargy or apathy. Cerenia can be used in combination with other medications, but its crucial to inform your veterinarian of all medications your dog is currently taking. Thanks! Interpretation of these study results is complicated by the health status of study animals. However, let's imagine for a moment the level of damage that may occur if a dog who has ingested toxin is administered Cerenia and the dog fails to vomit. For Prevention of Acute Vomiting in dogs 7 months of age and older: Administer CERENIA Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily until resolution of acute vomiting. Following is more in depth information about the side effects of Cerenia in dogs. The drug information leaflet though fails going into more specific details which may be insightful for concerned puppy and dog owners. One specific long term use is to prevent vomiting in cats with renal failure. On top of diarrhea, some dogs also developed blood in their stools. Maropitant is a neurokinin 1 (NK1) receptor antagonist which acts by inhibiting the binding of substance P, a neuropeptide of the tachykinin family. In people, topical exposure may elicit localized allergic skin reactions, and repeated or prolonged exposure may lead to skin sensitization. The concomitant use of Cerenia with other protein bound drugs has not been studied in dogs. But your veterinarian will determine if it continues to be the best route of care for your pet. Tags: cerenia for dogs, cerenia for dogs side effects, cerenia injection for dogs side effects. However, its important to administer Cerenia at least an hour before the motion sickness-inducing activity to ensure its effectiveness. Cerenia, or maropitant citrate, is a newer medication that can be given to your dog in injectable form under the skin or orally in a tablet. In people, topical exposure may elicit localized allergic skin reactions, and repeated or prolonged exposure may lead to skin sensitization. However as doses increase (20-50 mg/kg PO), dose proportionality is re-established. Placebo (n=106 ) Cerenia (n=107 ) # dogs. Diarrhea. What are the side effects of cerenia in dogs? Also, while its good to pack snacks and plenty of water for your pet, allocate these in the appropriate amounts. Cerenia or maropitant citrate is an FDA-approved antiemetic medication used for treating acute vomiting in dogs and cats and motion sickness.. The only common side effect of Cerenia includes pain on injection, which resolves within seconds. These work hand-in-hand with other treatment options to help you pet be pain-free and happy. Besides, Cerenia can also cause the dog to experience severe drowsiness. However, the information leaflet mentions that in the field study Cerenia was given for the prevention of acute vomiting without referencing whether dogs were entirely healthy beforehand. Cerenia generic name maropitant, is often prescribed to dogs with a history of acute vomiting. Cerenia has not be evaluated whether it is safe to usein pregnant or nursing animals. How long do side effects of Cerenia last? The most common side effect of Cerenia for dogs, or maropitant, is vomiting and drooling. Required fields are marked *. In a study of canine veterinary patients taken on a one-hour car journey and treated with either Cerenia Tablets at a minimum dose of 8 mg/kg BW or placebo tablets 2 hours prior to the journey, 67 of 122 (55%) of dogs vomited during the journey when treated with placebo while 8 of 122 (7%) vomited during the journey after treatment with Cerenia Tablets. J Vet Pharmacol Ther. Rarer side effects include lethargy, decreased appetite, diarrhea, allergic reactions, uncoordinated walking, and convulsions. In case of accidental ingestion, seek medical advice. If your dog experiences vomiting or diarrhea while taking Cerenia, they may become dehydrated. The medication needs a change to become fully absorbed and start working before your dog gets into a moving vehicle. Other Cerenia side effects in dogs include inflammation of the ear (3 dogs out of 206, 1.5 percent), endotoxic shock (2 dogs out of 206, 1 percent), blood in urine (2 dogs out of 206, 1 percent) excoriation, presence of erosion or ulceration caused by scratching, biting or rubbing (2 dogs out of 206, 1 percent). Make sure your vet knows whether your dog is on other medications while taking Cerenia. Cerenia is generally well tolerated by dogs, especially at lower doses, but some dogs will vomit up the pill right after swallowing it. The most common side effects seen in dogs and cats administered CERENIA are pain/vocalization (injectable), depression/lethargy, anorexia, anaphylaxis, ataxia, convulsions, hypersalivation, and vomiting. document.getElementById( "ak_js_2" ).setAttribute( "value", ( new Date() ).getTime() ); Canna-Pet produces the only legal, veterinarian-recommended, non-prescription CBD products for animals. Discover how to stop the behavior. Prevention of Vomiting Due to Motion Sickness (minimum of 8 mg/kg) Adverse Reaction. If your dog experiences these symptoms, its important to monitor them closely and contact your vet if they persist. Also, dehydration can lead to other side effects that can make for one long ride for both you and your pet. Even with doses exceeding the recommended dose, side effects are rare. This appears to happen when Cerenia is preserved with a preservative known as metacresol. There are other factors involved with prescription medication. Cerenia works by blocking a specific receptor in the brain called NK1. Cerenia is the first and only FDA-approved medication prescribed by veterinarians for dogs to help treat and help prevent vomiting caused by motion sickness. More serious effects that are less frequent include increased body temperature, changes in behavior, seizures, and excessive drooling. Acute vomiting symptoms include continuous vomiting, blood in the vomit or stool, pain, and weakness. Cerenia is not recommended for use in dogs less than 16 weeks old. According to a published study, oral maropitant is commonly used off label in cats at the same dose (1 mg/kg q24h), which differs from the labeled dose for dogs (2 mg/kg), probably due to the difference in . The drug information leaflet for Cerenia lists death as an adverse reaction in a US field study evaluating dogs administered Cerenia. Email The side effects of Cerenia for dogs is something for dog owners to watch for so to take prompt action should any arise. From time to time, your pup may vomit when at home, too. What are the precautions to take when administering Cerenia to dogs? Cerenia can also be used as a mild form of pain relief. Can Cerenia be used to prevent motion sickness in dogs? Acute vomiting symptoms include continuous vomiting. In vivo model studies in dogs have shown that maropitant has antiemetic effectiveness against both central and peripheral emetogens including apomorphine, and syrup of ipecac. This will help you determine if its an ongoing problem or a one-time event. www.petmd.com/pet-medication/maropitant-citrate. However, there are other ways your pet may have a more comfortable ride when traveling as well. Cerenia is a medication that has been used for many years in veterinary medicine to treat nausea and vomiting in dogs and cats. US Patents: See US 6,222,038; US 6,255,320. It's effective for about 24 hours. Cerenia is given orally. One dog in the 24 mg/kg/day group died of unknown causes on study day 2 and a dose dependent increase in occurrence and severity of bone marrow hypoplasia and lymphoid depletion was observed histologically. If youre introducing your pet to the medication for the first time, its wise to set out on a test drive before hitting the road for the real trip. Using Cerenia every day eventually risks depleting a dog's reserves of dopamine in their central nervous system leading to tremors (think Parkinsons disease). If your pet has accidentally overdosed on Cerenia, side effects may be similar, including loss of appetite, bloody stool, and diarrhea. Will my dog have to take Cerenia for the rest of his life? Another European study revealed similar results. The most common side effects of Cerenia include drowsiness, lethargy, and diarrhea. Call your vet or pharmacist if you have additional questions or concerns about the use of Cerenia. If your dog is suffering from acute vomiting, it may not always happen indoors, which means you may not always be privy to it right away. Urinary recovery of maropitant and its major metabolite was minimal (<1% each). Masking the symptoms leads to delayed diagnosis and treatment. It depends on other medications, age, breed, general health, and other physical concerns or risks your veterinarian detects. This can include symptoms like swelling, hives, or difficulty breathing. But when at home, it could be indicative of a variety of things. Additionally, leukopenia characterized by a neutropenia and a trend toward decreasing plasma phosphorus values was seen. Cerenia is generally safe for use in puppies over the age of eight weeks. The rare side effects of Cerenia can include: Diarrhea Anorexia (no appetite) Hematuria (blood in the urine) Hypersalivation (excessive drooling) These symptoms may include hives, swelling of the facial area, and/or difficulty breathing. Injectable maropitant is approved for the treatment of vomiting in cats, administered at a dose of 1 mg/kg IV or SC q24h for 5 days. Do some investigating to determine the cause of the vomiting. In some cases, prolonged use of Cerenia may lead to digestive issues, such as diarrhea or loss of appetite. This means that roughly 3.9 percent were affected by the runs. Also, your pet may have a serious allergic reaction if hes never taken Cerenia before. The same is true for pregnant or nursing dogs since it is not yet . This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The most common side effects seen in dogs and cats administered CERENIA are pain/vocalization (injectable), depression/lethargy, anorexia, anaphylaxis, ataxia, convulsions . In a study of 275 canine patients presented to veterinary hospitals with a history of acute vomiting, dogs were initially administered Cerenia Injectable Solution or placebo on Day 0. A placebo is not a medication, it is justa harmless medication without any physiological or therapeutical effect. In the most severe case, dogs may act as though they are experiencing a burning sensation. social@canna-pet.com The drug also works to control nausea and vomiting due to the relationship between the eyes and vestibular system. The good news is that Cerenia has been shown to be very effective at alleviating as well as to prevent car sickness in dogs. For many, dogs are like another member of the family and rarely are left behind regardless of the destination. From his dog training facility to kennels to neighbors who look after your pet from time to time, give them the medical history they may need when caring for your pet. In addition to these rare side effects, cats may also experience abnormal breathing, recumbency (laying down and unable to get up), vomiting, panting, and muscle tremors. If your dog experiences any side effects or new signs of illness while taking Cerenia, contact your veterinarian. There is limited information available on the use of Cerenia in pregnant or nursing dogs. Try to keep your pets diet as all-natural as possible. The safety of Cerenia has also been assessed when used concurrently with other common therapies, such as vaccinations, anthelmintics, dewormers, diagnostics, antibiotics, and anti-inflammatories. As the name implies, activation of the vomiting center leads to vomiting. When looking at dogs given the placebo, six out of 69 developed diarrhea. He or she will determine if Cerenia is a good option for your pet or decide what alternatives there might be. To make the trips enjoyable for all, find out what your dog needs to have a safe and comfortable ride. Many different medications use CYP as part of the process of being cleared from the body. If you have concerns due to a longer, upcoming trip, ask your veterinarian what options you have to prevent motion sickness vomiting. Fifty six Beagle dogs (28 males and 28 females) approximately 16 weeks of age were administered Cerenia Tablets orally once daily for 15 days at 0, 2, 6, and 10 mg/kg. However, this can be cured, though by getting the dog lots and lots water. A dose dependent increase in severity of bone marrow hypoplasia was observed histologically. Additional side effects to look out for may be things like changes in behavior (such as lethargy), a lack of coordination, and convulsions. Cerenia is only prescribed for dogs to prevent vomiting due to motion sickness. Yes, Cerenia can be used to prevent motion sickness in dogs. It's more likely the stress that's causing it - a normal reaction in dogs to any kind of stress. From time to time, your pup may vomit when at home, too. Veterinary Secrets 2022 Bestie PawsLower Manhattan, New York, NY 10038, USA. Cerenia's generic active ingredient Maropitant Citrate is an antiemetic (the drug that is effective against vomiting and nausea, and treatment for motion sickness) used to treat vomiting and motion sickness in dogs and cats. If it is the result of your dogs diet, discuss alternatives with your veterinarian to introduce or eliminate foods as needed. Acute vomiting may be the result of a change in diet, allergic reactions to food, inflammation, parasites, tumors, liver disease, adrenal gland disease, or heat stroke. or stool, pain, and weakness. Well follow up with a 25% off coupon code! If your dog is already prone to napping, you may notice that they become even more lethargic after taking Cerenia. Its up to you to weigh the pros and cons of side effects and determine how you want to progress with use. Countless puppies love chewing walls and their corners. Other Cerenia side effects in dogs include inflammation of the ear (3 dogs out of 206, 1.5 percent), endotoxic shock (2 dogs out of 206, 1 percent), blood in urine (2 dogs out of 206, 1 percent) excoriation, presence of erosion or ulceration caused by scratching, biting or rubbing ( 2 dogs out of 206, 1 percent). Home / Adverse Drug Reactions / Cerenia for Dogs Side Effects. The hepatic metabolism of maropitant involves two cytochrome P-450 isoenzymes: CYP2D15 and CYP3A12. The influence of concomitant drugs that may inhibit metabolism of Cerenia has not been evaluated. The following adverse reactions were reported during US studies for the prevention of vomiting due to motion sickness in dogs treated with Cerenia Tablets at a minimum of 8 mg/kg orally one time. To reduce the risk of these side effects occurring, dog owners should talk to their veterinarians about the correct dosage for their pets. The absolute bioavailability of maropitant was much higher following SC injection (91% at 1 mg/kg) than after PO administration (24% at 2 mg/kg). Possible Side Effects of Cerenia Consult with your veterinarian or seek immediate veterinary medical attention if vomiting continues despite treatment with Cerenia. Always confirm storage requirements by reviewing the label. If your dog has been prescribed Cerenia for acute vomiting and continues to vomit or is unable to take the medication because of it, then call your veterinarian right away. Buy Our Products at Local Retailers & Veterinarians. The most common side effects seen in dogs and cats administered CERENIA are pain/vocalization (injectable), depression/lethargy, anorexia, anaphylaxis, ataxia, convulsions, hypersalivation, and vomiting. Oral bioavailability may be underestimated due to the presence of nonlinear kinetics and the resulting longer T seen after intravenous (IV) administration. In most cases, your veterinarian may instruct you to not give extra or double doses. This receptor plays a crucial role in triggering vomiting and nausea. Maropitant is the non-proprietary designation for a substituted quinuclidine. CERENIA starts working quickly to prevent or treat your pet's vomiting. No specific monitoring is required for this medication, but your veterinarian may recommend routine testing depending on your pets' individual needs, other medications they may be on, and/or the issue that initially caused your pet to be placed on this medication. Complications may occur as well insmall dog vomiting because of an intestinal obstruction from ingesting sharp pieces of plastic. Cerenia can cause side effects like constipation, diarrhea, and increased thirst in some dogs. The following adverse reactions were reported during the course of a US field study for the prevention of acute vomiting in dogs treated with Cerenia Tablets at a minimum of 2 mg/kg orally and/or Injectable Solution at 1.0 mg/kg subcutaneously once daily for up to 5 consecutive days: Other clinical signs were reported but were <0.5% of dogs. Lets take a closer look. Take your dog for a walk and let him get out his energy prior to traveling, especially if youre going to be on a long flight or on a tight schedule when driving. In dogs, direct side effects from this medication are rare, but may . This effect can be reduced by keeping the medication refrigerated. Acute vomiting in dogs is more extreme and often requires the care of a veterinarian for effective treatment. Systemic clearance of maropitant following IV administration was 970, 995, and 533 mL/hr/kg at doses of 1, 2 and 8 mg/kg, respectively. Gabapentin (brand names: Neurontin, Aclonium, Equipax, Gantin, Gabarone, Gralise, Neurostil, Progresse) is an anti-seizure and pain medication that is used with other medications to treat seizures and is also used to treat chronic pain, primarily nerve pain. These concerns are not unfounded, considering that the drug information leaflet lists several potential side effects some of which can be quite scary. Cerenia is not recommended for use in dogs less than 16 weeks old. Despite its effectiveness, some pet owners . For personalized dosage instructions, talk to your veterinarian. Another side effect of Cerenia is loss of appetite. If you notice any unusual behavior in your dog while theyre taking Cerenia, its important to let your vet know right away. Cerenia (maropitant citrate) is the first and only FDA-approved veterinary medication to safely and effectively treat vomiting in dogs and cats and prevent vomiting due to motion sickness in dogs. Disclaimer: These statements have not been evaluated by the U.S. Food and Drug Administration. Side Effects of Cytopoint Injection for Dogs. Cerenia is a safe and effective drug for the treatment of vomiting in dogs. The body is often an amazing, yet underestimated entity when it comes to curing itself naturally. In studies, Cerenia has proven to be so effective, that even dogs who were given powerful emetics (substances known to cause vomiting) such as syrup of ipecac or apomorphine, failed to vomit courtesy of this drug. How does cerenia work? In laboratory model studies, Cerenia Tablets dosed at a minimum of 2 mg/kg BW reduced the number of emetic events associated with established neural (central) and humoral (peripheral) stimuli. Speak with your veterinarian about what to do if you forget to give a dose of Cerenia (maropitant citrate). Drug & Food Interactions Yes, there are several alternatives to Cerenia for treating nausea and vomiting in dogs. As with many other medications, Cerenia may cause side effects in some dogs, although many dogs may not develop them. Denamarin for dogs is a supplement given to pets that need liver support. The side effects of Cerenia for dogs is something for dog owners to watch for so to take prompt action should any arise. Finally, take as many breaks as you can. Cerenia may interact with certain drugs, including antibiotics and pain medications, so its important to disclose any medication your dog is taking to prevent any potential adverse reactions. Uses of Maropitant Citrate (Cerenia) for Dogs and Cats; Maropitant citrate is used to treat vomiting and prevent vomiting associated with motion sickness in dogs. Cerenia is primarily used to control nausea and vomiting in cats, including motion sickness. Frequent breaks - like every 30 or 45 minutes on a long trip - can also help set the mental reset button. Vomiting is a side effect of something else. Efficacy and safety of maropitant, a selective neurokinin 1 receptor antagonist, in two randomized clinical trials for prevention of vomiting due to motion sickness. Veterinary Record Open 2018;5:e000262. When prescribed, your dogs doctor will review all the side effects and potential risks to look out for. Cerenia is the only drug approved by the FDA for use in dogs to help prevent and treat vomiting caused by motion sickness. Frequently reported side-effects of this drug include hyperactivity, muscle restlessness, or drowsiness, as well as constipation in dogs. Whether your dog develops side effects from the Cerenia may vary based on several factors. PetMDs medications content was written and reviewed by veterinary professionals to answer your most common questions about how medications function, their side effects, and what species they are prescribed for. It is a prescription drug, which means that it needs to be prescribed by a licensed veterinarian, so you'll hardly find it over the counter somewhere.. Cerenia works in a way that it blocks particular receptors that cause vomiting, thus effectively . How can I tell if my dog is allergic to Cerenia? Even if you have one dog that uses Cerenia for vomiting due to motion sickness, consult with your veterinarian first before using it for another pet. The most common side effects of Cerenia include drowsiness, lethargy, and diarrhea. Cerenia is also an ocular irritant. There were 16 dogs (8 males and 8 females) in the 0 and 24 mg/kg groups and 8 dogs (4 males and 4 females) in the 8 mg/kg group. Package insert / product label It specifically targets the part of the brain that triggers vomiting (called the emetic center). Cerenia is prescription only. How long do the side effects of Cerenia last? For many, dogs are like another member of the family and rarely are left behind regardless of the destination. The most common side effects of Cerenia in dogs are drowsiness and lethargy. Continuous vomiting is an alert that there is something yet uncovered that is making your pet ill. An emergency visit to the veterinary clinic likely will be necessary. If this should occur, it will require emergency veterinary attention, which is an important to consider wherever you are traveling. Dont feed your dog up to one hour before giving him Cerenia and plan to give it to him approximately two hours before disembarking. An accumulation ratio of 1.5 was observed following once-daily use of maropitant for five consecutive days at 1 mg/kg (SC) or 2 mg/kg (PO). Dogs given a placebo though were also reported to suffer from hypersalivation. When in the car, its most likely due to motion sickness. However, its essential to consult with your veterinarian before giving your dog any new medication or supplements. The study shows that out of 69 dogs 2 developed a lack of appetite which is 2.9 of the total placebo-tested dogs. For other uses of this medication, please follow the directions on the drug label or as provided by your veterinarian. Even in reports of death from Cerenia in dogs,it is difficult to prove the cause of death unless the dog owners elects to have an autopsy done. " And, you want to take extra precautions if your dog has liver problems. Frequently Asked Questions. Cerenia, Accessed 17 Nov. 2017. Following administration of apomorphine (central emetic stimuli), vomiting was observed in 33% (4 of 12) of Beagle dogs treated with Cerenia Tablets and 100% (12 of 12) of Beagle dogs treated with placebo tablets. Its a powerful drug that works by blocking certain receptors in the brain and gastrointestinal tract. As with many other medications, Cerenia may cause side effects in some dogs, although many dogs do not develop them. Theyre easy on the digestive system and can also potentially help with other disorders like. Do some investigating to determine the cause of the vomiting. Cerenia is primarily used to treat nausea and vomiting caused by motion sickness, chemotherapy, and other medical conditions that affect the digestive system. . Dogs given a placebo though apparently were not free from being affected. Anxiety. While it might be tempting to share your snacks when on the road, it might not be the healthiest for your pet, especially if his stomach is more sensitive when traveling. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Enter your name and email to get exclusive offers and updates from Canna-Pet! 1-800-PetMeds explains the medication comes in four different sizes to accommodate dogs of all sizes, and it is a once daily medication that can be administered for up to five days. Cerenia peach-colored tablets are scored with a break line, and contain 16, 24, 60 or 160 mg of maropitant as maropitant citrate per tablet. This is about 8 percent of researched dogs. Possible Side Effects. Side effects of Cerenia may include drowsiness, lethargy, lack of appetite, and diarrhea. Use with caution in dogs with hepatic dysfunction. Due to this effect on the brain, Cerenia is a potent drug that can treat and prevent vomiting from a wide variety of causes. The injectable formulation is FDA approved for use in both dogs and cats, but the tablets are only approved by the FDA for use in dogs at this time. Other side effects may include vomiting lethargy and loss of appetite. Substance P is found in significant concentrations in the nuclei comprising the emetic center and is considered the key neurotransmitter involved in emesis.1 By inhibiting the binding of substance P within the emetic center, maropitant provides broad-spectrum effectiveness against neural (central) and humoral (peripheral) causes of vomiting. Considerations CERENIA is most effective in preventing acute vomiting associated with . Giving Cerenia to a dog with a blockage may temporarily stop the vomiting, while the plastic may cause intestinal perforationand life threatening peritonitis. Did you know? CAUTION: Federal (USA) law restricts this drug to use Information on how to report an adverse reaction can be found here: Reporting Animal Drugs. On top of this, your dog can be lethargic. Although tempting, its not recommended to hide it in food like hot dogs or cheese because it may affect the absorption and effectiveness rate. Fortunately, most vets are quite thorough in ruling out underlying causes of vomiting in dogs that need to be addressed before thinking of administering a powerful drug as Cerenia. Dogs used in the study were weaned early, minimally acclimated to the test facility, many of the dogs in the study tested positive for coccidia and some tested positive for canine parvovirus. Most veterinarians believe Cerenia injectable stings less if kept in the refrigerator. This way you can monitor how well your dog is responding to the medication and if its a suitable option long-term. For those who travel frequently with their pets, you most likely already have a routine down. Although hepatic first-pass metabolism contributed to the relatively low bioavailability after an oral dose, prandial status does not significantly affect the extent of oral bioavailability. Not all dogs are automatically good candidates for Cerenia. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. There were 8 dogs (4 males and 4 females) in the 2 mg/kg group and 16 dogs (8 males and 8 females) in all other groups. Behavioral changes. Uncommon side effects include: Allergic reaction Diarrhea Poor appetite Lethargy Uncoordinated walking Tremors Injectable Cerenia may cause pain and swelling at the injection site. This content shouldnt take the place of advice by your vet. Cerenia is fairly new drug that may be given as an injection or given by mouth to dogs who are suffering from nausea and vomiting. The vestibular system is found in the inner ear and is responsible for gathering information about balance and motion. The medication is designed to be given once a day for four to five days and typically will substantially reduce nausea and vomiting. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Does cerenia make dogs lose their appetite? Cerenia Tablets were used safely in dogs receiving other frequently used veterinary products such as fluid and electrolyte replacement solutions, antimicrobial agents, vaccines, antacids, and antiparasitic agents. Some dogs may also experience loss of appetite, vomiting, or abdominal pain.