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An alpha value of P<0.05 was considered statistically significant. Luteal phase support was continued to week 10 when -hCG tests were positive. tive value of - hCG levels following a day 5 embryo transfer in comparison to predictive values after a day 3 embryo transfer. Yes, those levels are good. I've been on endomentrin since before fet. I can't remember my exact HCG numbers but doctor said they were very high! The patients age was not proven to be of significant influence, the hCG level slightly decreased with higher age. For my case, I should have more 8000 after two days? Poikkeus P, Gissler M, Unkila-Kallio L, Hyden-Granskog C, Tiitinen A. Obstetric and neonatal outcome after single embryo transfer. Accessibility We strive to provide you with a high quality community experience. Today (8/28/19, so 10 days post transfer) I had bloodwork done and got the exciting call that I am pregnant! a: ROC curve analysis of -hCG for clinical pregnancies; b: ROC curve analysis of -hCG for live births, ROC curves for predicting pregnancy outcomes by fold increases in serum -hCG levels over 48h. a: ROC curve of the -hCG fold increase for clinical pregnancies; b: ROC curve analysis of a -hCG fold increase for live births. higher values can be misleading too (multiples, later miscarriage) so stay balanced.Your value is within the normal range and you should be . Wow congratulations! On the contrary, an increasing frequency of abortions depending on the increasing age of the mother was once again confirmed. 2003;80:135963. Yes 12 days. Please specify a reason for deleting this reply from the community. 2016 May 20;(5):CD011537. official website and that any information you provide is encrypted For patients with a regular menstruation cycle, the natural cycle was the first choice and blastocysts were transferred 5days post-ovulation. 4 weeks LMP: 5 - 426 mIU/mL. By using this website, you agree to our Congrats on your 6 month old twin girls! This study was supported by the National Natural Science Foundation of China (No.81801532, to HYL and No.81701518, to YY) and Scientific Research Program of The Third Affiliated Hospital of Guangzhou Medical University (No.2017Q15, to YXW). First, the patients studied had a -hCG test 14days after embryo transfer. To examine patients after embryo transfer for predictive influence of the human chorionic gonadotropin (hCG) level on the probability of finishing pregnancy with delivery. Our research had merely included patients with initially low serum -hCG levels, instead of all pregnant women, since there have been many studies like that. There are other medical reasons that could be behind an unusually high beta hCG. Our previous study investigated the likelihood of live births with serum levels of -hCG <100 mIU/ml 14days after day 3 embryo transfer, which showed that the live birth rate was only 4.3%. Retrospective study. HCG reaches its peak level around 8 to 11 weeks after conception and levels then decline, remaining steady for the rest of the pregnancy. The rate at which serum total beta-subunit human chorionic gonadotropin increases after embryo transfer is a predictor of the viability of pregnancy and an identifier of determinants of pregnancy. My nurse told me today that she made an error in my gestational age calculation (I knew it!) Second, the number of embryos that were successfully transferred varied from one to two. Im officially six weeks and 2 days. When this happens, a woman's body begins to produce the pregnancy hormone (hCG) from cells in the developing placenta. Thanks Nescio. It is important to determine beta-hCG levels regardless a potential bleeding since bleeding can occur during early pregnancy. Fertimed, Fertility Treatment Centre, Olomouc. Hi there - I just completed my first IVF cycle. When an initial serum -hCG is <58.8 mIU/ml, luteal phase support should be discontinued and serum -hCG measured with ultrasound one week later. My HCG levels 14 days after a frozen embryo transfer was 3700 !!! For these reasons, it is very important to make individualized follow-up plans according to different serum -hCG intervals. The present research possesses the following advantages. Among patients having a clinical pregnancy, about 60% were early miscarriage and 12.4% were ectopic pregnancy (data not shown). Reprod BioMed Online. I am pregnant with identical twin boys! In principle, Id say that everything is ok with you. I'm 40 years . But many successful pregnancies do start out with a lower beta hCG level. The influence of other factors: age (patients 20-50), number of transferred embryos (one, two and more) and the length of cultivation on the probability of finishing pregnancy with delivery or loss and the possibility to predict multiple pregnancy was also related to the known hCG value. MeSH A beta hCG level of over 100 is generally considered a good, positive result. Beta is in 3 days (1 Feb 2018). Setting: When is your ultrasound? A total of 312 patients had serum -hCG levels <300 mIU/ml 14days after blastocyst transfer, among which, 18.6% were live births, 47.4% were early miscarriages, 22.8% were biochemical pregnancies and 9.6% were ectopic pregnancies. Values about 130 mIU/ml indicate that youre 3-4 weeks pregnant. The spontaneous miscarriage rate was, therefore, 19.8% (22/111). In order to follow pregnancy outcomes, an increased number of serum -hCG tests are required; however, no appropriate follow-up plans have been suggested according to current scientific research. Serum -hCG levels and fold changes in -hCG levels over 48h were applied to predict clinical pregnancy as well as live births by plotting Receiver Operating Characteristic (ROC) curves. Good luck! We transferred a 4AA and 4BA, and their now sleeping in their room. Im so worried and confused. Morning sickness or nausea typically start in the second month of pregnancy, so it's not a symptom women normally experience in the 2-week wait after a fresh or frozen embryo transfer. Conclusions: For that reason the data was analysed through a multinomial logistic model vs. multinomial distribution of a mistake and generalised logistic link function. The threshold for live births was 108.6 mIU/ml with an AUC of 0.649, a sensitivity of 93.1% and a specificity of 37.0%. If 14 days after the aspiration (ovulation) beta-hCG is negative, there is no implantation. Early Serum hCG in IVF: Are We Trending in the Right Direction? Receiver operating characteristic (ROC) curves were plotted to explore the threshold of predicting clinical pregnancy and live births. sharing sensitive information, make sure youre on a federal Then i start having cramps which are very much like my menses cramps with on n off headaches. Press question mark to learn the rest of the keyboard shortcuts. There were no statistical differences between the groups in terms of the number of embryos transferred, the protocols of endometrial preparation, days of embryo transfer and endometrial thickness. Conclusion: Result was negative. Congratulations to you. Am I pregnant or not plz tell me. Wishing you a happy smooth pregnancy! I did CVS with my only child who is nearly 3 yrs. Before 2017;37:395400. A Chi-squared test was used to compare rates. The author confirms that the work described has not been published before; that its publication has been approved by all co-authors; that its publication has been approved (tacitly or explicitly) by the responsible authorities at the institution where the work is carried out. Singh N, Begum AA, Malhotra N, Bahadur A, Vanamail P. J Hum Reprod Sci. Create an account or log in to participate. Nausea. It's produced by your placenta after conception. 2023 BioMed Central Ltd unless otherwise stated. An official website of the United States government. I am currently 23 w tomorrow with twins. The spontaneous miscarriage rate was, therefore, 19.8% (22/111). Most of them were biochemical pregnancies (77.8%) and the remainder were early miscarriages (13.9%) and ectopic pregnancies (8.3%). Early Maternal Serum -human Chorionic Gonadotropin Measurements After ICSI in the Prediction of Long-term Pregnancy Outcomes: A Retrospective Cohort Analysis. 2016 May 20;(5):CD011537. All authors read and approved the final manuscript. Regardless, congratulations on your pregnancy! Best of luck to you and congratulations! 5. Embryo transfer: As a very important step in the fertilization process, the doctor will transfer embryos when the uterine lining has enough thickness and good quality, favorable for development when the embryo is placed in the uterus. I'd be happy with a healthy singleton. If the level was between 300 and 600, the ongoing pregnancy rate . Group Leaders arent expected to spend any additional time in the community, and are not held to a set schedule. I'm 33, but my OB tested me anyway and it is so reassuring! For thawing blastocysts, the top of the Cryotop containing the embryos was placed in a ThawingSolution for 1min at 37C. This is all very nerve racking. Yadid IM, Criscuolo TS, Santos JF, Giordano LA. Cycles where women underwent IVF with subsequent autologous fresh or frozen embryo transfer (ET), had a serum hCG >5 mIU/mL 8 or 10 days after ET, and had an US performed between 5 0/7 and 6 6/7 weeks that did not demonstrate a viable multiple gestation . The cookie is used to store the user consent for the cookies in the category "Analytics". Get the IPS Communities App for iPhone now. There can be a higher initial hCG trend increase with multiples, says Maureen Baldwin, M.D., MPH, an assistant professor of Obstetrics and Gynecology at Oregon Health and Science University . Initially low serum -hCG levels 14days after frozen blastocyst transfer indicated minimal chances of live birth. If you get an abnormal result you will not know which baby is potentially affected. Then after 2 days I repeated test it is now 97.79. Clin Endocrinol (Oxf). This study was approved by the ethics committee of the Third Affiliated Hospital of Guangzhou Medical University. Epub 2020 Oct 9. Thank you Shwhite. After my positive test, my clinic made me do three blood tests to watch the rise . -, Fertil Steril. inviTRA Copyright 2023 by Eureka Fertility. This prospective study was designed to assess the predictive value of a 14-day post-ET hCG level with pregnancy outcome and multiple gestation pregnancies. The sensitivity of the assay was 1.2 mIU/ml, with an intra-assay coefficient of variation of 7%. 1992 Aug;58(2):373-7 https://doi.org/10.1186/s13048-020-00732-6, DOI: https://doi.org/10.1186/s13048-020-00732-6. 5 weeks LMP: 18 - 7,340 mIU/mL. Methods: Group Black's collective includes Essence, The Shade Room and Naturally Curly. I would have done PGS but my embryos were NOT biopsied prior to freezing. 2. Part of I am new to this whole experience and found so much helpful info! But a blood test can detect it earlier. I had it done at Cedar Sinai with Dr. Williams, who has done about 27,000 CVS procedures and has had good results compared to other clinics. Why do you say your numbers are on the low side? HHS Vulnerability Disclosure, Help You numbers are not off the charts high. tomorrow, Friday the 8th, cause she wants to make sure its doubling.. My doctor has no idea what it could have been. CAS The effects of low-dose human chorionic gonadotropin combined with human menopausal gonadotropin protocol on women with hypogonadotropic hypogonadism undergoing ovarian stimulation for in vitro fertilization. Totally 8788 patients with serum -hCG >25mIU/mL 14days after frozen blastocyst transfer were screened and 312(3.5%) of them with low serum -hCG levels (i.e., 5299 mIU/ml) were included in the study. Thank you. A supportive and positive community to discuss your IVF journey. In my case I was transferring 5d embryo, and the hcg level was drawn after 2 weeks, I suppose this is the kinda normal for me? lol congrats :) hope you have a smooth pregnant and please update is either way :). The hCG level has to rise appropriately (it doubles every 3 days or so in early pregnancy) till it reaches around 1500 mIU/mL. Article Federal government websites often end in .gov or .mil. Create an account to follow your favorite communities and start taking part in conversations. Judging by my HCG blood test results, it looks like both of them stuck. Sals1980 4 years ago 17 Replies Pregnancy test 4 days after embryo transfer The authors declare that they have no competing interests. To approach this question we, evaluated - hCG values on day 16 after oocyte retrieval for both groups using a receiver operating characteristic (ROC) curve. I am not part of the fertility board but I will look into it. The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not the user has consented to the use of Cookies. Below are the average hCG levels during the first trimester: 3 weeks LMP: 5 - 50 mIU/ml 4 weeks LMP: 5 - 426 mIU/ml 5 weeks LMP: 18 - 7,340 mIU/ml The risk of adverse pregnancy (AP) outcomes such as ectopic pregnancy (EP), biochemical pregnancy (BP) and spontaneous abortion (SA) is greater in women undergoing ART compared with natural pregnancy. But using fresh eggs, the result in the IVF success rate calculator drops to 10.8%. In some IVF cycles, fresh embryos are transferred, while in other cases, frozen embryos can also be transferred to the uterus. Just went in for my ultrasound and saw we had 2 sticky babies! What should hCG levels be 14 days after embryo transfer? Cookies policy. The other one was smaller. Is it normal for after 2 weeks? The fold increase in clinical pregnancies and live births in our research was lower than those found in Sungs study. Early Serum hCG in IVF: Are We Trending in the Right Direction. Your post will be hidden and deleted by moderators. Blastocyst transfer was done 5days post-ovulation. For patients with an initially low -hCG, the most important consideration is to determine whether it is a clinical pregnancy. If you did a frozen embryo transfer: The beta hCG quantitative blood test is ordered 9-13 days after your embryo transfer, depending on the developmental stage of the embryo when . Is it a good level? Day 11: The embryo is surrounded by fluid inside the amniotic sac. An immunochemiluminometric assay was undertaken to assay for -hCG (Architech i2000SR; Abbott Laboratories Inc., Chicago, IL, USA). Below 1,200 mIU/ml, hCG usually doubles every 48-72 hours, but 35%+ is still normal. The HCG hormone level in the blood doubles every 48-72 h. If the HCG level doubles well, this indicates that the cells of the embryo are dividing well . MeSH 3 4 Also, the loss rate with CVS (and amnio) is provider -dependent so make sure you find a doctor that has ton a ton of themexperienced practitioners can have much lower rates of loss, like 1/1000. You may very well see 2 babies at your first ultrasound! I was just curious what #'s you all got (if you were being monitored because of trouble conceiving) and how many babies that turned out to be. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. For the -hCG fold increase over 48h, the cut-off for clinical pregnancy was 1.4 with an AUC of 0.899, a sensitivity of 90.3% and a specificity of 77.8%. In our research, we calculated the -hCG fold increase over 48h according to the second test and found that a value of 1.9 was the optimal threshold to discriminate live births from non-live births. A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. I had another beta yesterday and 48 hours later and came back 270. Wow, your levels at 12dp5dt were very high. Craciunas L, Tsampras N, Coomarasamy A, Raine-Fenning N. Cochrane Database Syst Rev. Statistical analysis was performed with SPSS version 22.0 software (IBM, Armonk, NY, USA). Although many previous studies have investigated the prediction of pregnancy outcomes by measuring serum -hCG levels after blastocyst transfer, no study has yet focused on pregnancy outcomes of patients with an initially low serum -hCG level. I had two five day embryos put in at age 43 and HCG was 1647 - 13dpt and 4451 - 15 dpt. A retrospective study was conducted at the Third Affiliated Hospital of Guangzhou Medical University to study patients whose serum -hCG levels were at 5299 mIU/ml 14days after frozen blastocyst transfer. In normal conception, -hCG levels are doubled every 48h, and consequently, this increased pattern is applied to discriminate normal pregnancy from a state of pathological pregnancy [1]. I didn't know the gestational age for frozen embryo transfers were from the day of embryo transfer. Location: Ryan Family Atrium, Robert H. Lurie Medical Research Center . Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. Thanks everyone! Serum -hCG assays were done 14days after embryo transfer. Epub 2016 Jul 22. Google Scholar. Let me share that one of my nurses had a first value of 5.2 and delivered her son! Rates of biochemical pregnancy loss, ectopic pregnancy, early and late miscarriages, live birth were comparable between the <38years group, and the >38years group (Table1). Then the blastocysts were placed into a Cryotop and placed immediately into liquid nitrogen. Had to wait until my ultrasound to confirm it was twins. Predictive value of initial serum human chorionic gonadotropin levels for pregnancies after single fresh and frozen blastocyst transfer. Many prior studies have explored the relationship between serum -hCG levels and pregnancy outcomes. Congrats. Best of luck to you too! Between 1,200 and 6,000 mIU/ml serum, the hCG usually takes 72-96 hours to double. The hCG level grows exponentially in the course of the 9th to 17th day after an embryo transfer (ET). I'm sorry to hear about the tissue, hopefully it's nothing to be concerned aboutwhen is your next ultrasound? ROC curve analysis showed that a predicted value of -hCG for clinical pregnancy was 58.8 mIU/ml with an area under the ROC curve (AUC) of 0.752, a sensitivity of 95.0% and specificity of 53.5%. Is super high good? It typically takes 48-72 hours after the embryo transfer for the embryo to implant. Kathiresan AS, Cruz-Almeida Y, Barrionuevo MJ, Maxson WS, Hoffman DI, Weitzman VN, Christie DR, Manko GF, Ory SJ. -, Br Med J (Clin Res Ed). 2021 Jul;28(7):1827-1838. doi: 10.1007/s43032-020-00347-8. The thresholds predicting clinical pregnancy and live births in these studies were higher than those in our study, which can be explained by the fact than only patients with a low -hCG were included in our research. hCG (Human Chorionic Gonadotropin) is the "pregnancy hormone." It is detected soon after implantation and typically doubles every 72 hours. I heard hcg doubles every 48 hours, does this apply to whatever baseline we have? Springer Nature. Your numbers at this stage are very strong. Vaginal progesterone (Crinone, Merck Serono, Germany 90mg qd) was given for luteal phase support in artificial cycles. My girls are 20 months now. Wang Q, Zhang R, Jia M, Luo L, Ding C, Li TC, Zhou C. Gynecol Endocrinol. If the hCG level was greater than 600, the multiple pregnancy rate was 100% (7/7). Most HPTs will pick up an HCG reading 11 or 12 days after the embryo enters the uterus. Nevertheless, they demonstrated that the 2.37- and 2.6-fold values respectively predicted 89.8% of clinical pregnancies and 72.7% of live births [1]. When the dominant follicle was 18mm, 800010,000IU of human chorionic gonadotropin (HCG) was given to induce ovulation. Bookshelf The Internet will tell you pretty much everything causes abnormalities to the point your head spinsit is hard, but especially for things like this that are completely out of control, try to give yourself a break with the worry. FOIA Rates of live birth, early miscarriage, biochemical pregnancy loss and ectopic pregnancy were analyzed according to the female patients age by Chi-squared analysis. Conversely, when the hCG on day 15 was below 150 mIU/mL and the ratio of hCG on day . Post embryo transfer symptoms vary with the origin of the embryos: if they are fresh, frozen, or from donated eggs. Objective: 1985 Oct 26;291(6503):1160-3 63, Duobao Road, Guangzhou, Guangdong, China, You can also search for this author in On 7th of June was 421. This can causes problems with interpretation of pregnancy tests done earlier than 14 days after an HCG injection. Good luck to you! J Assist Reprod Genet. I am very curious, 2 weeks post IVF 5-day, 2 blastocyst embryo transfer and beta results, Blastocyst day 5 transfer on 23rd January. Note that once you confirm, this action cannot be undone. Bethesda, MD 20894, Web Policies Its rising, but not doubling up, not even close. ; chorionic gonadotropin; hCG. Epub 2017 Oct 16. 2015;103:152631 e12. The lower limits of serum-borne -hCG levels were 64.9 mIU/ml for singleton live births, 145.1 mIU/ml for twin live births, 15.3 mIU/ml for early miscarriage, and 5.3 mIU/ml for ectopic pregnancies. To keep all these cookies active, click the Accept button. Home Forums Infertility & Fertility Treatments Post Embryo Transfer Signs & Symptoms. 2 While mild to moderate cramping can be normal, call your doctor if the cramping is not relieved by over-the-counter pain medications . Days 7 and 8: Fetal development continues, and hCG continues to be secreted. Asked for Female, 27 Years 2080 Views v. After 5 years of trying to conceive without any success, My husband and I had decided to try IVF and we were very lucky to success on the first try. The whole rechecking causes me a lot of stress and agony.. Hello again, Im completely scared to death I had another beta test yesterday, June 16th and the result was 2078. !..is it a miscarriage??? My hCG is 575 (again, this is 10 days post embryo transfer). I had 460 @ 10dpt, 3500 @ 14dpt and was twins. First, we only analyzed patients with low serum -hCG levels instead of investigating all pregnant patients, which will be helpful in developing appropriate suggestions of follow-up for this group of patients. I read others beta levels and I think that mine are extremely low. Thank you for sharing. HCG Levels during the first trimester. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. A few previously reported studies investigated the prediction of pregnancy outcomes by serum -hCG levels over various days following vitrified-warmed blastocyst transfer. Reprod BioMed Online. So there will not be a heart beat yet. Zhang Q, Yan J, Tang R, Gao X, Zhang B, Chen ZJ. The single -hCG value >410.8IU/L indicated that 76.62% of live births and a value below that threshold, resulted in 80.72% of non-live births [8]. PubMed \). Fertil Steril. statement and For patients with -hCG levels of 550 mIU/ml, no live birth occurred. Kathiresan AS, Cruz-Almeida Y, Barrionuevo MJ, Maxson WS, Hoffman DI, Weitzman VN, et al. Delay of embryo transfer to day 5 results in decreased initial serum beta-human chorionic gonadotropin levels. Slightly: The first HCG level after ivf embryo transfer gives only a rough idea of success. Twins & Multiples: Your Tentative Time Table. It reaches its peak by 8-11 weeks of pregnancy and levels off. 1989 Feb;51(2):304-9 An hCG level under 5 is considered negative. The burse said numbers dont provide that info, onlu u/s.so now we just waiting. Google Scholar. Two -hCG parameters were examined in relation to live birth: 1) "doubling" defined as -hCG doubling over 48 h and 2) "reaching 100" defined as a -hCG 100 mIU/mL by 15 days after oocyte retrieval (AOR). After an embryo transfer procedure, it takes around 10-14 days to see the IVF results. Has anyone had such high numbers after an embryo transfer? However, the serum -hCG levels of patients with live births (median: 196 mIU/ml) was significantly higher than that of patients with non-live births (median: 140 mIU/ml, P=0.0001; Table3). Home urine test: Depending on when implantation occurs, pregnancy may be able to be detected in certain early home pregnancy tests as soon as five days after a transfer of a 5-day embryo. Possibility of live birth in patients with low serum -hCG 14days after blastocyst transfer, \( {\left(\frac{\mathrm{HCG}1}{\mathrm{HCG}0}\right)}^{\raisebox{1ex}{$2$}\!\left/ \!\raisebox{-1ex}{$\mathrm{days}$}\right.} ROC curves for predicting pregnancy outcomes by serum -hCG levels 14days after blastocyst transfer. Hope to see you back on site if you confirm multiples! Prior to 14 days, it is not possible to differentiate between hCG from the trigger shot and hCG from the embryo. Disclaimer. On June 4th, my beta was 136. Unauthorized use of these marks is strictly prohibited. Please enable it to take advantage of the complete set of features! If within 14 days of the embryo transfer, uncontrollable bleeding similar to that of a period appears, it is essential to go to, or call, the reproductive center where the treatment was performed. Patients undergoing in vitro fertilization (IVF) and ET were monitored by serum quantitative hCG levels 14 days after ET. Powered by DCIP Consulting. On day 12 following embryo transfer, serum hCG level of each patient was determined by a fluoroimmunometric assay system. HCG0 was defined as serum -hCG concentrations that were measured 14days after embryo transfer; HCG1 was defined as serum -hCG levels in the second test, and the term days represented the interval between the two -hCG tests. 2. What does an hCG level measure? I am 41 years old now. I'm afraid it is a negative result indeed. Xiong F, Li G, Sun Q, Chen P, Wang Z, Wan C, et al. Careers. This cookie is set by GDPR Cookie Consent plugin. Oron G, Esh-Broder E, Son WY, Holzer H, Tulandi T. Predictive value of maternal serum human chorionic gonadotropin levels in pregnancies achieved by in vitro fertilization with single cleavage and single blastocyst embryo transfers. At my age, I definitely need to screen for abnormalities. Oron G, Shavit T, Esh-Broder E, Weon-Young S, Tulandi T, Holzer H. Predictive value of serum HCG concentrations in pregnancies achieved after single fresh or vitrified-warmed blastocyst transfer. Prognostic value of beta-human chorionic gonadotropin is dependent on day of embryo transfer during invitro fertilization. 2011;96:13626. Fertil Steril. Craciunas L, Tsampras N, Coomarasamy A, Raine-Fenning N. Cochrane Database Syst Rev. Thank you for your response! Normal HCG levels range widely in early pregnancy. Here are my results9dpt = 238, 10dpt = 557, 12dpt = 1473. Hi! In case you don't get a ton of answers here, you might get more there. Were you part of the fertility board? And congrats and have a happy healthy pregnancy either way. Type, duration, causes of infertility, and age of patients, B-hCG levels on the sixteenth day after embryo transfer, the number of embryos, and pregnancy outcome were assessed. I hope all goes well. Of course only the ultrasound will tell you for sure but lots of things can happen! The hCG value was 678 (564-815) IU/l1 on the 14th day after ET in pregnancy ended in delivery, 321 (216-477) IU/l on average in abortion, 82 (51-132) IU/l in biochemical pregnancy and 1070 (737-1554) IU/l in multiple pregnancy. Eskandar MA, Al-Shahrani M, Shaamash A, El-Emain M, Al-Ahmad M, Payodon B. J Clin Med Res. One hundred eleven patients had positive serum quantitative hCG levels 14 days post-ET; 89/111, or 80.2%, had ongoing pregnancies. 312 patients had serum -hCG levels <300 mIU/ml at 14days after frozen blastocyst transfer, among which, 18.6% were live births, 47.4% were early miscarriages, 22.8% were biochemical pregnancies and 9.6% were ectopic pregnancies. Beta hCG levels are increasing as you have witnessed yourself after the 4th of June. For the record, my HCG levels were 768 11dpt. Allows SESSION variables to be stored on the web server. This is why your clinic will. The value in predicting live births was 1.9, with an AUC of 0.803, a sensitivity of 88.5%, a PPV of 97.4% and an NPV of 92.3%. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. It does not store any personal data. For frozen embryo transfer, the cut-off value was 137399IU/L for clinical pregnancy and 212411IU/L for live births 1112days after embryo transfer [6,7,8]. Vitrification and thawing kits (KitazatoBiophamaCo. Ltd. Shizuoka, Japan) were applied for blastocyst cryopreservation and thawing. Many women on this board (mused included) have done the NIPT with twins at the recommendation of our doctors. Results: One hundred eleven patients had positive serum quantitative hCG levels 14 days post-ET; 89/111, or 80.2%, had ongoing pregnancies. So that means that by 14dp5dt, your hcg levels were probably very close to mine. Nearly 50% (47.4%) of the patients were early miscarriage and the rate of ectopic pregnancy was as high as 9.6%. This retrospective study included patients that had received a frozen blastocyst transfer in the Department of Reproductive Medicine of the Third Affiliated Hospital, Guangzhou Medical University (Guangzhou, China), between January 2014 and October 2019. First HCG level after 14 days of transfer is 964. When the hCG level on day 15 was 150 mIU/mL and an hCG day 22/hCG day 15 ratio of 15 with a specificity of 94% and sensitivity of 47% for normal pregnancy.